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Description

The 2020 systematic review by Galeano and colleagues across 34 eligible studies confirmed the mechanism: PDRN promotes physiological tissue repair through salvage-pathway nucleotide recycling and A2A receptor activation [32]

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This combined activation mechanism stimulates insulin secretion while concurrently increasing energy expenditure via glucagon pathways

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As a dual agonist, it targets both the GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

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